Cosmosil
5C18-P-MS
This
column is based on an ultra-pure silica gel (more than 99.99%)
with carbon content of only 8.5%. Therefore the retention
of polar compounds is relatively longer than that on the C18-MS-II
or C18-AR-II. This column is also suitable for
the analysis of a wide range of chemical compounds including
polypeptides.
MATERIAL
CHARACTERISTICS |
|
COSMOSIL
5C18-P-MS |
Silica
gel |
high
purity porous spherical silica |
Average
particle size |
5µm |
Average
pore size |
approx.
120Å |
Specific
surface area |
approx.
300m²/g |
Stationary
phase |
monomeric
type octadecyl group |
End
capping treatment |
near-perfect
treatment |
Carbon
content |
approx.
8.5% |
Comparison data using different COSMOSIL ® C 18 columns |
The COSMOSIL ® 5C 18 -P-MS gives quicker separation of most samples compared with other COSMOSIL ® 5C 18 type columns. However, there is a characteristic by which the polar compounds are retained relatively longer on the COSMOSIL ® 5C 18 -P-MS.
|
Separation of di-substituted benzene isomers |
| Because their characteristics (eg. polarity) and structure is very similar, isomers of di-substituted benzene are one of the most difficult samples to separate. It is possible to separate them at a high probability by using either any or a combination of three types of COSMOSIL ® C 18 (MS-II, AR-II, P-MS). |
|
