Research on ESS60® and Health

Although ESS60® was isolated several decades ago, research into the effects of the molecule on human health is still in the early stages.

Most studies have been performed in cells or animals, and only a handful of human studies have been done.

For clarity, ESS60® is a proprietary version of the carbon molecule processed for Human consumption.  We think of Carbon 60 as a molecule for industrial purposes with peer-reviewed published research proving that when improperly processed it is harmful.  ESS60® is Carbon 60 that has been processed for safer human consumption.  In each of the papers below the Carbon 60 has been processed in such a way that we would consider it ESS60®.

The chart below summarizes the current state of the ESS60® research landscape in seven health and wellness areas. Each field has been given a grade based on the number of studies that showed an effect of ESS60® and whether they were studied in humans or animals:

Field/Condition Grade Notable Studies


A 2010 randomized, placebo-controlled trial examined the use of ESS60®-containing skin cream in 23 Japanese women and the effect on wrinkles and skin roughness.

In a small 2011 study, researchers studied the effects of a face gel containing ESS60® on acne.

Studies done in mice have also examined the ability of ESS60®-containing solutions to block the effects of ultraviolet radiation and promote hair growth when applied to the skin.

Inflammatory conditions

In 2019, research was published that examined the effects of an ESS60® derivative on joint damage and inflammation in rats with arthritis.

 A 2016 study explored the ability of an ESS60® compound to regulate inflammation in a mouse model of eczema.

Cognitive function

Rat models of amyloidosis and Alzheimer’s disease have been used to examine the effects of ESS60®, delivered directly into the brain, on learning and memory and cognitive function.

Cancer, cancer treatment effects

Studies have explored the effects of ESS60® derivatives on tumor growth, metastasis, and survival in mice and rats.

A 2020 study examined the ability of ESS60® to protect against lung damage in mice treated with bleomycin, an anti-cancer drug.

Muscle fatigue

A 2017 study explored the effects of ESS60® on muscle fatigue and endurance in rats.


Researchers in 2012 and in 2020 examined the ability of ESS60® to affect the lifespan of rats.


Studies in rat models of diabetes have examined the ability of ESS60® to prevent neuronal and kidney damage resulting from hyperglycemia.

In a 2020 study, researchers explored whether ESS60® affected the gut microbiome and how that influenced insulin resistance.